National Freedom Party (NFP) leader Zanele kaMagwaza-Msibi died in hospital on Monday, the party confirmed.
NFP MP Ahmed Shaik Emam said the party was reeling from the news.
He said kaMagwaza-Msibi had been admitted to an Umhlanga hospital in Durban.
KaMagwaza-Msibi, a former deputy minister, cited ill health when she resigned from Parliament in 2019.
This is a developing story.